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随着液化石油气(简称LPG)在家庭中的普遍使用,其污染对健康的影响已引起人们的关注。有LPG气态及滤膜收集提取物致突变性和肺部毒性研究的报道,但LPG燃烧产物直接作用于整体动物而产生毒性危害,国内外报道较少。为此,我们进行本实验以探讨其对小鼠细胞免疫功能的影响。1 材料和方法 1.1LPG 由中国石化总公司长岭炼油厂提供。平均分子量51.60,由C_3-C_4的链烃组成。 1.2动物和染毒本院实验动物中心提供的7～8周龄昆明种小鼠,雌雄各半,体重18～24g,随机分为对照组、单灶燃烧染毒组和双灶燃烧染毒组,每
With the widespread use of liquefied petroleum gas (LPG) in the home, the health impact of pollution has drawn much attention. There are reports on the mutagenicity and lung toxicity of LPG in gas and membrane-collected extracts. However, LPG combustion products directly exert toxic effects on whole animals and are rarely reported at home and abroad. To this end, we conducted this experiment to investigate its impact on mouse cellular immune function. 1 Materials and methods 1.1LPG provided by China Petrochemical Corporation Changling refinery. The average molecular weight of 51.60, composed of C_3-C_4 chain hydrocarbons. 1.2 Animals and Infection The Kunming mice of 7-8 weeks old provided by the Laboratory Animal Center of our hospital were randomly divided into a control group, a single-burning combustion group and a double-burning combustion group ,each