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目的:探讨精神分裂症后抑郁患者社会支持与预后的关系。方法:按社会支持量表(SSRS)评分将86例精神分裂症后抑郁患者分为社会支持好组(SSRS评分>40分)和社会支持差组(SSRS评分≤40分)各43例,在两组入院时和治疗8周后,采用汉密尔顿17(HAMD-17)量表和阴性症状量表(PANSS)进行抑郁评分和临床症状评分,并采用Pearson相关分析探讨SSRS评分与HAMD评分与PANSS总分的相关性。结果:社会支持好组SRSS评分与差组比较差异有统计学意义(P<0.05);社会支持好组在治疗8周后,PANSS总分和HAMD评分低于差组(P<0.05);社会支持好组治疗有效率高于差组(P<0.05);经Pearson相关性分析,SSRS评分与HAMD评分和PANSS评分呈显著负相关关系(P<0.05)。结论:社会支持与患者预后有显著关系,获得更好社会支持的精神分裂症后抑郁患者预后效果更好。
Objective: To investigate the relationship between social support and prognosis in patients with post-schizophrenia depression. Methods: Eighty-six patients with post-schizophrenia depression were divided into three groups according to the scale of social support (SSRS): good social support group (SSRS score> 40 points) and poor social support group (SSRS score≤40 points) At admission and after 8 weeks of treatment, depression scores and clinical symptom scores were calculated using the Hamilton 17 (PANSS) scale and the Hamilton Symptom Scale 17 (HAMD-17), and Pearson correlation analysis was used to investigate the relationship between SSRS score and HAMD score and PANSS Relevance of points. Results: The scores of SRSS in the good social support group were significantly different from those in the poor group (P <0.05). After 8 weeks of treatment, the scores of PANSS and HAMD in the good social support group were lower than those in the poor group (P <0.05) There was a significant negative correlation between SSRS score and HAMD score and PANSS score (P <0.05) by Pearson correlation analysis. Conclusion: There is a significant relationship between social support and patient prognosis. Patients with post-schizophrenia depression receiving better social support have a better prognosis.