论文部分内容阅读
目的：观察十六角蒙脱石和雷尼替丁联合治疗消化性溃疡的疗效。方法：１３５例经胃镜证实的消化性溃疡病人（男性１０１例，女性３４例，年龄４０±ｓ１１ａ），分成４组。Ａ组３８例，用十六角蒙脱石３．０ｇ，ｐｏ，ｔｉｄ，雷尼替丁１５０ｍｇ，ｐｏ，ｂｉｄ；Ｂ组３４例用雷尼替丁１５０ｍｇ，ｐｏ，ｂｉｄ；Ｃ组３１例用奥美拉唑２０ｍｇ，ｐｏ，ｑｄ；Ｄ组３２例用胶体次枸橼酸铋１１０ｍｇ，ｐｏ，ｑｉｄ。４组均以４ｗｋ为一个疗程。结果：Ａ组的愈合率超过Ｂ组及Ｄ组（Ｐ＜０．０５），与Ｃ组相仿（Ｐ＞０．０５），且Ａ组药物有清除幽门螺旋杆菌的作用。结论：十六角蒙脱石和雷尼替丁联合治疗消化性溃疡疗效较佳。
Objective: To observe the effect of hexagonal montmorillonite and ranitidine in the treatment of peptic ulcer. Methods: 135 patients with peptic ulcer confirmed by gastroscope (101 males and 34 females, age 40 ± s11a) were divided into 4 groups. A group of 38 patients with hexagonal montmorillonite 3.0g, po, tid, ranitidine 150mg, po, bid; B group of 34 patients with ranitidine 150mg, po, bid; Omeprazole 20mg, po, qd; D group 32 cases of colloidal bismuth sub-citrate 110mg, po, qid. 4 groups were 4wk for a course of treatment. Results: The healing rate of group A was higher than that of group B and group D (P <0.05), similar to that of group C (P> 0.05). The drug of group A was able to clear H. pylori. Conclusions: Hexagonal montmorillonite and ranitidine combined treatment of peptic ulcer better curative effect.