论文部分内容阅读
目的:观察刺五加总甙神阙穴位贴敷疗法的抗睡眠剥夺作用.方法:健康青年男性19～22岁)志愿者24名,完全随机分为4组(正常组、模型组、处理组、对照组),除正常组外剥夺全部睡眠48 h,以自制刺五加总甙复方制剂于神阙穴处贴敷,观察其对睡眠剥夺人体的心理影响以及对皮质醇、睾酮等血液生化指标的影响.结果:48 h睡眠剥夺后,刺五加总甙穴位贴敷皮质醇浓度增高值(44.482±96.065 nmol/L)低于对照组增高值(146.809±71.075 nmol/L),自评抑郁量表增加值(2.833±16.746)亦低于对照组增加值(20.417±10.358),差异均具有显著性(P＜0.05),而睾酮浓度降低和焦虑量表增加值,处理组与对照组无明显差异(P＞0.05).结论:刺五加总甙穴位贴敷可调节机体反应水平和心理承受能力,具有对抗睡眠剥夺的作用.,Objective: To investigate the efficacy of extal application of Eleutherosides ointment on Shenque (CV 8) for treating sleep deprivation. Methods: Twenty four healthy young male volunteers at the age of 19-22 years old were randomly allocated to 4 groups (normal, model, treatment and control groups). Sleep was deprived for 48 hours except the normal group. Self-made Eleutherosides compound preparation was applied extally on Shenque (CV 8), to observe its influence on psychology and blood biochemical indices of cortisol and testosterone of the human body in sleep deprivation. Results: After sleep deprivation for 48 hours, an increment in cortisol concentration was lower in the Eleutherosides group (44.482 ± 96.065 nmol/L) than in the control group (146.809 ± 71.075 nmol/L); an increment in the self-evaluated depression scale was also lower in the Eleutherosides group (2.833 ± 16.746) than in the control group (20.417 ± 10.358). There were significant differences (P＜0.05). But, there was no significant difference between the treatment group and control group (P＞0.05) in the decrement of testosterone concentration and the increment of the anxiety scale. Conclusion: Extal application of Eleutherosides preparation on Shenque (CV 8) can regulate the stress reaction level and psychological endurance of the human body and produce an effect to resist sleep deprivation.