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目的:探讨特布他林加赛庚啶对婴儿气喘和咳嗽的疗效,并与氨茶碱作比较。方法:治疗组31例(男性21例,女性10例,年龄15±s6mo)采用特布他林0.065mg/(kg·d),赛庚啶0.25mg/(kg·d),均分为3次口服。对照组28例(男性16例,女性12例,年龄16±6mo)用氨茶碱3~5mg/(kg·d),分3次口服。2组综合治疗(地塞米松、镇咳药、抗生素、吸氧)大致相仿。结果:2组总显效率分别是55%和25%,治疗组止咳平喘作用显著优于对照组(P<0.05)。结论:特布他林加赛庚啶治疗婴儿气喘和咳嗽的安全性强、疗效较好。
Objective: To investigate the therapeutic effect of terbutaline and cyproheptadine on infant asthma and cough, and to compare with aminophylline. Methods: 31 cases of treatment group (21 males, 10 females, age 15 ± s6mo) were treated with terbutaline 0.065mg / (kg · d), cyproheptadine 0.25mg / (kg · d) Oral 3 times. Control group of 28 patients (16 males and 12 females, aged 16 ± 6mo) with aminophylline 3 ~ 5mg / (kg · d), 3 times orally. Two groups of comprehensive treatment (dexamethasone, antitussive, antibiotics, oxygen) are roughly the same. Results: The total effective rates in two groups were 55% and 25%, respectively. The effect of relieving cough and asthma in the treatment group was significantly better than that in the control group (P <0.05). CONCLUSIONS: The combination of terbutaline and cyproheptadine is safe and effective in infants with asthma and cough.