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食管癌是世界上常见的恶性肿瘤之一。其形成是多因素的作用、多基因的变化和多阶段发展的结果,而肿瘤的发生主要是基因表达异常造成的[1]。基因表达异常包括基因突变、基因缺失、基因过度表达和基因表型改变等,其中基因表型改变包括DNA
Esophageal cancer is one of the most common malignancies in the world. Its formation is a multifactorial role, multi-gene changes and the results of multi-stage development, and the tumor is mainly caused by abnormal gene expression [1]. Abnormal gene expression, including gene mutations, gene deletion, gene overexpression and gene phenotypic changes, including gene phenotypic changes include DNA