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目的分析连云港市预防接种不良反应发生特点,为进一步降低预防接种不良反应的发生提供科学依据。方法对网络直报和月报告一览报表上报的772例预防接种不良反应相关信息进行流行病学统计分析和数据汇总。结果共有20种生物制品发生772例不良反应,总发生率为36.18/10万,发生年龄主要集中在0～岁组和1～岁组,两年龄组发生数占总发生数的65.02%,发生的不良反应分类以一般反应为主,共666例,占总数的86.27%,临床诊断以发热红肿硬结为最多,共651例,占总数的84.33%。结论连云港市预防接种信息管理系统中的AEFI管理网络直报系统运转正常,且敏感性不断提升。各县区均有不良反应报告,多种疫苗均可发生,但发生率并不相同。应关注不良反应发生率较高的人群和苗种,通过采取针对性的干预措施、加强基层接种人员的业务培训、严格掌握疫苗接种禁忌症和强化卫生知识宣传等手段和途径,有效减少和预防接种不良反应的发生。
Objective To analyze the characteristics of adverse reactions of vaccination in Lianyungang City and provide scientific basis for further reducing the occurrence of adverse reactions of vaccination. Methods The epidemiological analysis and data summary of 772 vaccination-related adverse reactions reported in the network direct report and monthly report list were collected. Results A total of 772 adverse reactions occurred in 20 kinds of biological products, with a total incidence rate of 36.18 / 100 000. The age of onset was mainly in 0 ~ group and 1 ~ group, with 65.02% in the two age groups occurring There were 666 cases, accounting for 86.27% of the total. The most common clinical diagnosis was fever and inflamed sclerosis, a total of 651 cases, accounting for 84.33% of the total. Conclusion The direct reporting system of AEFI management network in Lianyungang vaccination information management system is in normal operation and its sensitivity is continuously increasing. All counties have reported adverse reactions, a variety of vaccines can occur, but the incidence is not the same. Should pay attention to people and seedlings with higher incidence of adverse reactions, through targeted interventions to strengthen grass-roots vaccination staff training, strict control of contraindications to vaccination and strengthening health knowledge and other means and ways to effectively reduce and prevent Adverse reactions occurred.