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现已充分证实人体免疫缺陷病毒(HIV)感染中枢神经系统,可致AIDS并发痴呆/亚急性脑病综合征。本文报告1个婴儿病例。足月产女婴,其母妊娠5个月时患带状疱疹。患儿7～8个月龄渐表现易怒、表情淡漠,9个月时双下肢张力增加,10个月时双上肢不灵活,肌阵挛阳性。对各种病毒血清学检查阴性。11个月时无微笑,无发言、肝肋下3cm,间歇性内斜视,四肢张力增高下肢更显著,腱反射亢进,头控制不良,颈屈肌无力,不能坐起,布氏征不对称。GOT(534U/L)、肌酸激酶(833U/L)、LDH(633U/L)增高。
It has been fully confirmed that human immunodeficiency virus (HIV) infection of the central nervous system can cause AIDS complicated with dementia / subacute encephalopathy syndrome. This article reports 1 infant case. Full-term baby girl, her mother suffering from herpes zoster at 5 months of pregnancy. Children 7 to 8 months of age showed irritability, apathy, at 9 months double lower limbs increased tension, 10 months when the upper limb is not flexible, myoclonus positive. Negative serological tests on various viruses. 11 months without a smile, no speech, liver ribs 3cm, intermittent esotropia, limbs increased tension lower limbs more significant, tendon hyperreflexia, head control poor, cervical flexor muscle weakness, can not sit up, Buss signs levy asymmetry. GOT (534U / L), creatine kinase (833U / L) and LDH (633U / L) increased.