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本文应用ELISA法对北京部分地区一般人群的血清幽门螺旋菌抗体水平进行了流行病学调查。发现抗体水平随年龄的增加而升高,60岁以上老人抗体阳性率达66.2%,而2l~30岁年龄组仅为27.1%;这恰与胃炎随年龄升高而发病率上升的现象相一致。在是否吸烟和饮酒的问题上,未见血清抗体水平有明显差异(P>0.05)。调查表明:幽门螺旋菌感染是本地区人群胃炎的病因之一;本地区人们一生中反复遭受幽门螺旋菌感染,从而造成随年龄升高感染率上升之现象。而吸烟和饮酒不影响幽门螺旋菌对人体之感染。
In this paper, the prevalence of serum H. pylori antibody in the general population in some areas of Beijing was investigated by ELISA. Antibody levels were found to increase with age, with antibody positive rates of 66.2% for those over 60 years of age compared to 27.1% for those 21 to 30 years old; this coincided with an increase in the incidence of gastritis with increasing age . There was no significant difference in serum antibody levels between smoking and drinking (P> 0.05). The survey shows that Helicobacter pylori infection is one of the causes of gastritis in people in this region. People living in this region repeatedly suffer from Helicobacter pylori infection, resulting in an increase of infection rate with age. Smoking and drinking do not affect Helicobacter pylori infection of the human body.