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目的探讨fish技术用于检测乳腺癌HER2基因扩增的临床应用价值。方法本次医学观察选择我院2010年1月至2012年1月之间收治的51例乳腺癌患者为观察对象,所有患者均接受fish技术进行HER2基因扩增检测,回顾分析患者的临床检测结果。结果 fish技术HER2基因有无扩增患者蛋白表达检测结果对比统计学差异明显(P<0.05)。结论由本次临床研究结果可知,fish技术应用于乳腺癌HER2基因扩增的临床检测过程中,具有较高的应用价值。
Objective To investigate the clinical value of fish technology in the detection of HER2 gene amplification in breast cancer. Methods The medical observation selected our hospital from January 2010 to January 2012 51 cases of patients with breast cancer were observed, all patients were receiving fish technology HER2 gene amplification detection, review the clinical test results of patients . Results There was statistically significant difference in the protein expression of the patients with or without amplification of HER2 gene (P <0.05). Conclusions From the results of this clinical study, we can see that fish technology has high value in the clinical detection of HER2 gene amplification in breast cancer.