论文部分内容阅读
目的研究对比厦门市一类疫苗与可替代的二类疫苗的疑似预防接种异常反应(AEFI)发生率,为了解疫苗安全性和提高预防接种质量提供依据。方法对2012—2014年厦门市AEFI监测系统报告的个案进行分析。结果吸附性无细胞百白破+HIB+IPV联合疫苗(“五联苗”)AEFI报告发生率79.1/10万,高于无细胞百白破(24/10万)和脊灰减毒活疫苗(7.4/10万)。乙脑减毒活疫苗(27.9/10万)与乙脑灭活疫苗(38.4/10万)、甲肝减毒活疫苗(12.1/10万)与甲肝灭活疫苗(13.9/10万)、脊灰灭活疫苗(7.8/10万)与脊灰减毒活疫苗的AEFI报告发生率均无统计学差异。结论五联苗替代无细胞百白破疫苗、乙脑灭活疫苗替代乙脑减毒活疫苗、甲肝灭活疫苗替代甲肝减毒活疫苗、脊灰灭活疫苗替代脊灰减毒活疫苗,不能降低AEFI报告发生率。
Objective To compare the incidence of suspected immunization inoculation (AEFI) between the first class vaccine and the second class vaccine in Xiamen City, and to provide evidence for the safety and vaccination quality of vaccines. Methods The cases reported by Xiamen AEFI monitoring system from 2012 to 2014 were analyzed. Results The incidence of AEFI was 79.1 / 100 000, higher than that of cell-free baobab (24/10) and attenuated by polio Live vaccine (7.4 / 100,000). Live attenuated attenuated live attenuated hepatitis A vaccine (12.1 / 100,000) and live attenuated hepatitis A vaccine (13.9 / 100,000), poliovirus Inactivated vaccine (7.8 / 100000) and live attenuated poliovirus AEFI report the incidence of no difference. Conclusions PentaTripping replaces cell free diphtheria vaccine, JE inactivated vaccine replaces JE attenuated live vaccine, HAV inactivated vaccine attenuates live attenuated hepatitis A vaccine, and poliomyelitis inactivated vaccine replaces poliovirus live attenuated vaccine, and can not Reduce the incidence of AEFI reports.