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患者男性,47岁,发现右拇指、指端背侧、指甲下,出现黑色斑,遂年加深变黑并扩展,局部皮肤增厚,粗糙三年余,无明显自觉症状,近年指甲变形,萎缩,偶有疼痛而于1992年5月,来我科就诊,体检:各系统检查未见异常,无内脏肿瘤病变发现,皮肤科情况:右大指指端背侧及甲下黑变,呈坏疽样,指甲萎缩、变形、变薄,甲床周围黑变皮肤增厚,增粗,延至第一指关节,境界清楚,病变皮肤表面似鹅绒样,乳头瘤状隆起,干燥兽皮样,局部无压痛,不红肿,指关节活动自如,血常规、肝、肾功能检验均正常范围,右大指 X 线摄片检查骨质无异常改变。临床印象:局限性黑棘皮病?恶变待排。病理报
Male patient, 47 years old, found right thumb, dorsal side of the finger, under the fingernail, black spots, darkening and darkening the following year, local skin thickening, rough more than three years, no obvious symptoms, nail deformation in recent years, shrinking , Occasional pain and in May 1992, came to our department for medical examination, physical examination: no abnormalities in the various system examinations, no visceral tumor lesions found, dermatological conditions: the right major finger refers to the dorsal and dorsal black, gangrene Samples, nails atrophy, deformation, thinning, black skin around the bed becomes thicker, thicker, extended to the first knuckle, realm clear, skin lesions like goose down, papillomatous uplift, dry skin, no local The tenderness, no redness and swelling, free movement of the knuckles, normal blood, liver, and kidney function tests were all within the normal range. The right thumb X ray examination showed no abnormal changes in bone quality. Clinical impression: limitations of black acanthosis? Pathology