1935年陈心陶教授首先在广州的家鼠肺和心脏中发现广州管圆线虫,此后世界各地陆续有动物受感染的报道。人因吞食含有本虫幼虫的中间宿主如螺类等而受感染,出现嗜酸性粒细胞增多性脑膜脑炎症状。1944年Nomura等在我国台湾省发现广州管圆线虫第一例人体病例,在脑脊液中找到了幼年成虫,其后在亚洲及太平洋岛屿上不断有散在性或暴发性流行的报 In 1935 Professor Chen Xindao first found in Guangzhou lungs and heart of rats, Rotifer, which has since been reported infected animals around the world. People are infected with an intermediate host, such as snail, which ingests larvae of this species, causing eosinophilic meningoencephalitis symptoms. In 1944, Nomura found the first human case of A. cantonensis in Taiwan Province of China and found juvenile adults in cerebrospinal fluid. Subsequently, there were continuously scattered or outbreaks of epidemic in the Asian and Pacific islands