食管癌根治术后预防性放射治疗的临床价值评价

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目的:分析食管癌根治术后预防性放射治疗的临床价值。方法:收集我院2011年3月-2012年4月期间诊治的食管癌患者76例作为研究对象,按照计算机数字随机分组的方式将患者分为试验组和对照组,每组38例,对照组患者单纯给予手术治疗,试验组患者手术后给予预防性放射治疗,对两组患者的治疗效果进行对比分析。结果:研究结果显示,对照组患者手术治疗后血糖以及CPR降低程度明显低于试验组,数据结果比较差异具有统计学意义(P<0.05)。对照组患者手术治疗后CD3、CD4程度明显低于试验组,数据结果比较差异具有统计学意义(P<0.05)。试验组患者手术结束后NK水平升高明显优于对照组,数据结果比较差异具有统计学意义(P<0.05);对患者实施为期两年的随访发现,试验组患者的1年生存率为94.74%,2年生存率为78.95%,对照组患者的1年生存率为81.58%,两年生存率为52.63%,试验组患者的1年生存率和2年生存率均显著高于对照组(P<0.05)。结论:管癌根治术后预防性放射治疗具有良好的临床效果,能有效提高患者的生存率,值得在临床上推广应用。 Objective: To analyze the clinical value of preventive radiotherapy after radical operation of esophageal cancer. Methods: A total of 76 patients with esophageal cancer diagnosed and treated in our hospital from March 2011 to April 2012 were enrolled in this study. Patients were divided into experimental group and control group randomly according to the computer number. Each group included 38 patients and control group The patients were treated with surgery alone. The patients in the experimental group were given preventive radiotherapy after operation, and the therapeutic effects of the two groups were compared. Results: The results showed that the blood glucose and CPR decreased significantly in the control group after operation, the difference was statistically significant (P <0.05). The levels of CD3 and CD4 in the control group were significantly lower than those in the experimental group after operation, the difference was statistically significant (P <0.05). The experimental group of patients with elevated NK levels after surgery was significantly better than the control group, the data were statistically significant differences (P <0.05); two-year follow-up of patients found that patients in the test group 1-year survival rate was 94.74 %. The 2-year survival rate was 78.95%. The 1-year survival rate was 81.58% in the control group and 52.63% in 2-year survival rate. The 1-year survival rate and 2-year survival rate in the experimental group were significantly higher than those in the control group P <0.05). Conclusion: The preventive radiotherapy after radical mastectomy has a good clinical effect, which can effectively improve the survival rate of patients, which is worth popularizing in clinic.
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