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Podophyllotoxone, 4β-hydroxy-2,3-en-apopicropodophyllin, and 4-deoxy-4β-azado-2,3-en-apo-picropodophyUin can easily transform to 4-hydroxy-dehydropicropodophyUin, dehydroanhydropicropodophllyin and4-amino-dehydropicropodophyllin respectively in different