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目的:探讨抗精子抗体(ASAb)、抗子宫内膜抗体(EMAb)和抗心磷脂抗体(ACAb),在引起不孕不育的过程中起到的作用。方法:用ELISA法检测ASAb,金标免疫斑点法检测EMAb和ACAb。结果:ASAb男性阳性率为13.1%,女性阳性率为28.3%。EMAb男性阳性率为3.1%,女性为15.1%。ACAb男性阳性率为7.4%,女性为14.8%。结论:ASAb、EMAb和ACAb是引起不孕不育的重要免疫因素。应加强对夫妻双方的免疫性抗体的检测。
Objective: To investigate the role of antisperm antibody (ASAb), anti-endometrial antibody (EMAb) and anticardiolipin antibody (ACAb) in the process of infertility. Methods: ASAb was detected by ELISA, and gold immunofluorescence assay was used to detect EMAb and ACAb. Results: The positive rate of ASAb was 13.1% in male and 28.3% in female. The positive rate of EMAb was 3.1% in males and 15.1% in females. The positive rate of ACAb was 7.4% in males and 14.8% in females. Conclusion: ASAb, EMAb and ACAb are the important immune factors that cause infertility. Should be strengthened on both spouses immune antibody detection.