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目的探索用鸡蛋内衣合并重组牛碱性成纤维细胞生长因子凝胶治疗外伤性鼓膜穿孔的疗效。方法把76例外伤性鼓膜穿孔患者随机分为两组,治疗组42例,对照组34例,两组均予抗生素预防感染。治疗组在此基础上,用鸡蛋内衣以重组牛碱性成纤维细胞生长因子凝胶为粘贴剂贴补鼓膜。观察60d,观察两组鼓膜穿孔愈合情况及愈合时间。结果治疗组在治愈率和治愈时间上均明显优于对照组,二者比较有显著性差异。结论鸡蛋内衣合并重组牛碱性成纤维细胞生长因子凝胶治疗外伤性鼓膜穿孔是一种切实可行,操作简便,经济的方法,值得临床推广。
Objective To explore the curative effect of using egg underwear combined with recombinant bovine basic fibroblast growth factor gel in the treatment of traumatic tympanic membrane perforation. Methods Totally 76 patients with traumatic tympanic membrane perforation were randomly divided into two groups: treatment group (42 cases) and control group (34 cases). Both groups were given antibiotics to prevent infection. On the basis of this, the treatment group was treated with the recombinant bovine basic fibroblast growth factor gel as the patch to patch the tympanic membrane with the egg underwear. Observed 60d, observed the tympanic membrane perforation healing and healing time. Results The treatment group was significantly better than the control group in the cure rate and cure time, the two were significantly different. Conclusions Egg underwear combined with recombinant bovine basic fibroblast growth factor gel for the treatment of traumatic tympanic membrane perforation is a feasible, simple and economical method which is worthy of clinical promotion.