胃肠道间质瘤(GIST)虽然是消化道最常见的间叶性肿瘤,但其发病率约为0.0014%,其中小于1 cm(微小GIST)可见于20%～30%老年人中。这些微小GIST是否代表着GIST的癌前病变尚不清楚。作者收集了170例肿瘤直径≤2 cm的GIST,分析了它们的免疫组化特征、分子生物学改 Although gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor in the digestive tract, the incidence is about 0.0014%, of which less than 1 cm (tiny GIST) can be seen in 20% to 30% of the elderly. Whether these tiny GISTs represent precancerous lesions of GIST is unclear. The authors collected 170 GISTs with tumor diameters <2 cm and analyzed their immunohistochemical characteristics, molecular biology