角膜移植术中,缝线材料与缝合方式是移植片能否透明愈合的重要因素之一。有关缝线毒性和组织反应已有国内外学者研究和报告。Aronson等,McMastan等,通过动物实验研究,认为10—0单丝尼龙线反应最小,8—0编织丝线反应最重。周道伐通过穿透性角膜移植术的临床观察,发现5—0丝线的缝线反应较9—0～10—0尼龙线重。本科在角膜实质埋线实验中发现,无论丝线或尼龙线都可以在角膜实质内存在而无明显反应,也 In corneal transplantation, suture material and suture method is one of the important factors of whether the graft can be transparently healed. About suture toxicity and tissue reaction have been domestic and foreign scholars research and report. Aronson et al., McMastan et al., Through animal experimental studies, found that 10-0 monofilament nylon yarn has the least reaction and 8-0 braided silk yarn has the most reaction. Thoughtful through the clinical observation of penetrating keratoplasty, we found that 5-0 thread suture reaction than 9-0 ~ 10-0 nylon thread weight. Undergraduate embedding in the cornea real embedding experiments found that both silk or nylon lines can exist in the cornea without significant reaction, but also