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目的观察肝动脉灌注化疗栓塞联合微波消融治疗中晚期肝癌48例临床疗效。方法选择2010年3月-2012年8月我院收治的96例中晚期肝癌患者,随机分为实验组和对照组,对照组单纯行肝动脉灌注化疗栓塞治疗,实验组行肝动脉灌注化疗栓塞联合微波消融治疗,比较两组患者近期疗效、甲胎蛋白下降水平及转移复发情况。结果治疗后实验组AFP平均下降水平明显高于对照组,治疗总有效率(68.8%)明显高于对照组(47.9%),差异有统计学意义。治疗1年后实验组转移复发率明显低于对照组。结论肝动脉灌注化疗栓塞联合微波消融治疗中晚期肝癌安全有效,可明显延长患者生存时间,降低转移复发率,值得临床推广使用。
Objective To observe the curative effect of hepatic arterial chemoembolization combined with microwave ablation on 48 cases of advanced liver cancer. Methods A total of 96 patients with advanced hepatocellular carcinoma who were treated in our hospital from March 2010 to August 2012 were randomly divided into experimental group and control group. The control group was treated with hepatic arterial chemoembolization alone. The experimental group received hepatic arterial chemoembolization Combined microwave ablation, compared the short-term efficacy of two groups of patients, the level of alpha-fetoprotein and metastasis and recurrence. Results After treatment, the average level of AFP in the experimental group was significantly higher than that in the control group. The total effective rate (68.8%) was significantly higher than that of the control group (47.9%). The difference was statistically significant. After 1 year of treatment, the recurrence rate of the experimental group was significantly lower than that of the control group. Conclusion Hepatic arterial chemoembolization combined with microwave ablation is safe and effective in the treatment of advanced hepatocellular carcinoma, which can significantly prolong the survival time and reduce the recurrence rate. It is worthy of clinical application.