本文报道了影响人类肿瘤手术标本顺铂浓度的因素。45例接受手术治疗的肿瘤患者，在术前5min～6hiv溶于50mL生理盐水的顺铂10mg·m－2。采取给药前、后0～45min和术后1，2，3h的去蛋白血样以及手术切除的肿瘤标本，以无火焰原子吸收分光光度法测定顺钥浓度。颅内肿瘤（IC）患者 This article reports on the factors affecting the cisplatin concentration in human tumor surgical specimens. Forty-five tumor patients undergoing surgical treatment were dissolved in 50 mL of normal saline, 10 mg·m-2 of cisplatin 5 min to 6 hiv before surgery. Deproteinized blood samples and surgically resected tumor specimens were taken before and after 0-45 min of administration, 1, 2, and 3 h after surgery, and the key-concentration was measured by flameless atomic absorption spectrophotometry. Intracranial tumor (IC) patients