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肿瘤转移是一个复杂的过程,具有明显的器官倾向性。随着对肿瘤转移认识的不断深化,人们发现肿瘤特异性转移与肿瘤的异质性和靶器官的作用密切相关。目前认为转移的瘤细胞与内皮细胞的特殊粘附及靶器官内生长因子对肿瘤细胞生长的影响,可能是造成器官特异性转移的主要机制。
Tumor metastasis is a complex process with obvious organ propensities. With the deepening understanding of tumor metastasis, it was found that tumor-specific metastasis and tumor heterogeneity are closely related to the role of target organs. Now that the special adhesion of metastatic tumor cells and endothelial cells and target organ growth factor on tumor cell growth may be the main mechanism of organ-specific transfer.