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近年来,随着化学因素、物理因素、生物因素及污染等多种因素的诱发,使恶性血液病的发病率逐渐增高,而目前对恶性血液疾病的早期发现、早期诊断及对患者的病情监测及治疗效果的评估,尚缺少一个较为理想的血清学监测指标。胸苷激酶1(thymidine kinase-1,TKl)能将脱氧胸苷转化为胸苷酸,是合成DNA的关键酶,是一种与细胞周期性分裂有关的血生化指标,可在多种肿瘤患者的血清中检测到,目前已发现的血清
In recent years, with the chemical factors, physical factors, biological factors and pollution induced by a variety of factors, so that the incidence of hematological malignancies gradually increased, and now the early detection of malignant hematological diseases, early diagnosis and monitoring of the patient’s condition And evaluation of the therapeutic effect, there is still a lack of an ideal serological monitoring index. Thymidine kinase-1 (TKl) can convert deoxythymidine into thymidylate, a key enzyme in the synthesis of DNA. It is a blood biochemical indicator related to cell cycle disruption. It can be used in various tumor patients Serum has been detected in serum so far