2. 您的位置
3. 首页
4. 期刊论文
5. AK4在大鼠雄性生殖系统中的表达特点及应激反应机制

AK4在大鼠雄性生殖系统中的表达特点及应激反应机制

来源 :烟台大学学报（自然科学与工程版） | 被引量 : 0次 | 上传用户：kingofking1

【摘 要】

：

系统分析了AK4在成年大鼠各主要组织(心、肝、脾、肺、肾、睾丸和附睾)及在不同周龄大鼠睾丸和附睾中的表达谱.RT-PCR及Western结果表明,AK4在各组织中呈泛在表达,且在睾丸中AK4水平从2周龄到4周龄逐渐上调,5周龄后表达趋于稳定;在附睾中,AK4在2周龄大鼠中不表达,从3周龄到4周龄表达逐渐上调,5周龄后表达基本趋于稳定.此外,构建了成年大鼠睾丸、附睾的热应激和氧化应激模型,与对照组相比,两个模型中AK4在睾丸和/或附睾组织中表达均显著上调.在应激条件下AK4的过表达对雄性生殖细胞起到一定的保

【作 者】

：

李岩 李建远 

【机 构】

：

烟台大学生命科学学院,山东烟台264005

【出 处】

：

烟台大学学报（自然科学与工程版）

【发表日期】

：

2022年2期

【关键词】

：

AK4 睾丸 附睾 热应激 氧化应激 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

系统分析了AK4在成年大鼠各主要组织(心、肝、脾、肺、肾、睾丸和附睾)及在不同周龄大鼠睾丸和附睾中的表达谱.RT-PCR及Western结果表明,AK4在各组织中呈泛在表达,且在睾丸中AK4水平从2周龄到4周龄逐渐上调,5周龄后表达趋于稳定;在附睾中,AK4在2周龄大鼠中不表达,从3周龄到4周龄表达逐渐上调,5周龄后表达基本趋于稳定.此外,构建了成年大鼠睾丸、附睾的热应激和氧化应激模型,与对照组相比,两个模型中AK4在睾丸和/或附睾组织中表达均显著上调.在应激条件下AK4的过表达对雄性生殖细胞起到一定的保护作用.本研究将为阐明雄性生殖系统中AK4在应激状态下参与的信号通路提供数据支持和理论依据.

其他文献

Global patterns of fern species diversity:An evaluation of fern data in GBIF

Despite that several studies have shown that data derived from species lists generated from distribution occurrence records in the Global Biodiversity Information Facility(GBIF)are not appropriate for those ecological and biogeographic studies that requir

期刊

ClimateData biasFernGBIFSpecies diversitySpecies list

Evidence for two types of Aquilegia ecalcarata and its implications for adaptation to new environmen

Spurs have played an important role in the radiation of the genus Aquilegia,but little is known about how the spurless state arose in A.ecalcarata.Here we aim to characterize the genetic divergence within A.ecalcarata and gain insights into the origin of

期刊

Aquilegia ecalcarataPhylogenyPopulation structureGene flowSpur loss

Non-host plants:Are they mycorrhizal networks players?

Common mycorrhizal networks(CMNs)that connect individual plants of the same or different species together play important roles in nutrient and signal transportation,and plant community organization.However,about 10％of land plants are non-mycorrhizal speci

期刊

ColonizationMycorrhizal networksNon-hostsTripartite interaction

Diversity and species-specificity of brood pollination of leafflower trees(Phyllanthaceae:Glochidion

Glochidion(Phyllanthaceae;leafflower trees)is a genus of trees which is widely reported to be pollinated by leafflower moths(Gracillariidae:Epicephala)in temperate and subtropical Asia,Australia,and the Pacific islands.However,the pollination ecology of G

期刊

GlochidionEpicephalaObligate pollination mutualismLeafflower—leafflower moth

Genome size evolution of the extant lycophytes and ferns

Ferns and lycophytes have remarkably large genomes.However,little is known about how their genome size evolved in fern lineages.To explore the origins and evolution of chromosome numbers and genome size in ferns,we used flow cytometry to measure the genom

期刊

Genome sizeFernsChromosome numbersHabitat typeWhole-genome duplicationsEvol

Oreocharis xieyongii,an unusual new species of Gesneriaceae from western Hunan,China

A new species,Oreocharis xieyongii T.Deng,D.G.Zhang&H.Sun,from Hunan Province,central China,is described.The combination of purple zygomorphic corolla with longer adaxial lobes and exserted sta-mens defines the species and discriminates it from all other

期刊

ChinaGesneriaceaeMorphologyPhylogenyTaxonomy

改进的G-布朗运动驱动的随机微分方程的稳定性

主要研究由G-布朗运动驱动的随机微分方程的稳定性问题,利用一致渐近稳定函数,提出了指数p-稳定性和指数p-不稳定性的新的充分条件,所得结果减弱了原有指数p-稳定性定理和指数p-不稳定性定理的条件约束.

期刊

G-布朗运动稳定性不稳定性一致渐近稳定函数

Identification and fine mapping of rtms1-D,a gene responsible for reverse thermosensitive genic male

Thermosensitive genic male sterility(TGMS)has been widely used in two-line hybrid rice breeding.Due to hybrid seed production being highly affected by changeable environments,its application scope is limited to some extent.Thus,it is of great importance t

期刊

Rice(Oryza sativa L.)Reverse thermosensitive genic male sterile(RTGMS)rtms1-D

基于反步滑模法的四旋翼飞行器的轨迹跟踪

研究了四旋翼飞行器的轨迹跟踪控制问题.首先根据经典的动力学模型建立惯性坐标系下带有扰动的四旋翼方程.其次将系统划分为姿态子系统和位置子系统,对姿态子系统的轨迹跟踪控制,采用反步控制与滑模控制相结合的方法,根据飞行器的欠驱动和强耦合特性,利用反步控制方法实现位置子系统的轨迹跟踪控制.然后对系统进行稳定性分析.最后通过仿真实验结果验证所提出控制方法的有效性.

期刊

四旋翼飞行器反步控制滑模控制轨迹跟踪

Intraspecific trait variation of woody species reduced in a savanna community,southwest China

Plants deploy various ecological strategies in response to environmental heterogeneity.In many forest ecosystems,plants have been reported to have notable inter-and intra-specific trait variation,as well as clear phylogenetic signals,indicating that these

期刊

Phylogenetic signalSavannaIntraspecific trait variation(ITV)Leaf phenologyCo