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目的提高临床肾综合征出血热(HFRS)早期诊疗水平,降低死亡率。方法回顾性分析2011年1月至2015年10月东莞市人民医院收治的住院确诊的94例HFRS患者的临床资料,对HFRS病情及预后,以及其与发热期血液系统指标的关系进行分析。结果 94例肾综合征出血热病例轻型病例22例,中型病例66例,重型病例2例,危重病例4例(因重型及危重型病例较少,统一合并为一组);在病情方面,轻型、中型及重型三组间白细胞数值依次升高,差异有统计学意义(P=0.02),提示白细胞数值与病情相关;在预后方面,存活组及死亡组两组间血小板数值比较,死亡组血小板明显降低,差异有统计学意义(P=0.03),提示血小板数量与预后相关。结论临床上应重视早期血象改变,为病情分级及预后提供依据,做到早诊断、早治疗,提高抢救成功率。
Objective To improve the early diagnosis and treatment of hemorrhagic fever with clinical renal syndrome (HFRS) and reduce the mortality rate. Methods The clinical data of 94 HFRS patients admitted to Dongguan People’s Hospital from January 2011 to October 2015 were retrospectively analyzed. The relationship between the HFRS condition and prognosis, and the hematological indicators during the fever period were analyzed. Results Of the 94 patients with hemorrhagic fever with renal syndrome, 22 were mild, 66 were medium, 2 were severe and 4 were critically ill (due to the less severe and critically ill cases and the unification into one group). In the condition, (P = 0.02), indicating that the white blood cell count was correlated with the disease. In terms of prognosis, the values of platelet count in the survival group and the death group were significantly higher than those in the death group Was significantly lower, the difference was statistically significant (P = 0.03), suggesting that the number of platelets and prognosis. Conclusions In clinic, attention should be paid to the early change of blood picture to provide the basis for the grading and prognosis of disease. Early diagnosis and early treatment should be done to improve the success rate of rescue.