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目的探讨磁共振弥散加权成像(DWI)对早产儿脑白质损伤的早期评价和诊断价值。方法收集2007年2月至2012年8月因缺氧而收入我院新生儿重症监护室(NICU)疑似早产儿脑白质损伤的早产儿57例,对其进行头颅B超检查,并同步进行DWI检查。结果 (1)早产儿脑白质损伤早期DWI脑室周围白质水肿区高信号。磁共振成像(MRI)呈T1WI呈低信号,T2WI呈高信号。(2)DWI诊断早产儿脑白质损伤的特异度为95%。结论 (1)DWI显示的双侧脑室周围白质对称性弥漫性高信号是脑白质损伤的最早期表现。(2)DWI能发现早期脑白质损伤病变,早产儿脑白质损伤早期临床表现缺乏特异性,建议常规行头颅MRI检查。
Objective To investigate the early evaluation and diagnostic value of magnetic resonance diffusion-weighted imaging (DWI) in white matter damage of premature infants. Methods From February 2007 to August 2012, 57 preterm infants admitted to our neonatal intensive care unit (NICU) with hypoxia and suspected white matter damage in preterm infants were examined by B-ultrasound and DWI an examination. Results (1) The early signs of white matter edema around the periventricular area in preterm infants with early white matter damage were high. Magnetic resonance imaging (MRI) was low signal T1WI, T2WI was high signal. (2) The specificity of DWI in the diagnosis of white matter damage in preterm infants was 95%. Conclusions (1) The diffuse hyperintensities of white matter symmetry in bilateral periventricular spaces by DWI are the earliest manifestations of white matter damage. (2) DWI can detect early lesions of white matter lesions, the early clinical manifestations of white matter damage in preterm children is not specific, it is recommended conventional brain MRI.