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目的急性心肌梗死早期测定脑纳素(BNP)在评价梗死后心功能的临床价值。方法急性心肌梗死患者急性期和恢复期分别测定BNP浓度,左室射血分数(LVEF)和心功能Killip分级。结果 LEVF≤40%组,Killip(Ⅲ-Ⅳ)组,血浆BNP浓度显著高于LVEF>40%(P<0.001),Killip(Ⅰ-Ⅱ)组(P<0.001)。结论急性心肌梗死患者早期血浆BNP浓度可以作为评价心肌梗死后心功能敏感指标,具有临床价值。
Objective To evaluate the clinical value of early detection of brain natriuretic peptide (BNP) in the evaluation of cardiac function after infarction in acute myocardial infarction. Methods BNP concentration, left ventricular ejection fraction (LVEF) and Killip classification of cardiac function were measured in acute and convalescent patients with acute myocardial infarction. Results The LEVF≤40%, Killip (Ⅲ-Ⅳ) and plasma BNP concentrations were significantly higher than those of LVEF> 40% (P <0.001) and Killip (Ⅰ-Ⅱ) groups (P <0.001). Conclusion The plasma BNP concentration in patients with acute myocardial infarction can be used as a sensitive index to evaluate the cardiac function after myocardial infarction, which has clinical value.