本文报道了女性同性性早熟111例,其中真性性早熟63例,假性性早熟48例。真性性早熟中主要包括特发性性早熟、中枢神经系统疾患和McCune-Albright综合征;假性性早熟主要包括乳房早熟、外源性性早熟及肿瘤。结合临床特征,讨论了真性与假性性早熟的临床鉴别诊断。用氯地孕酮治疗真性性早熟43例, This article reports 111 cases of female homosexual precocity, of which 63 cases of true precocious puberty, 48 cases of pseudo-precocious puberty. True precocious puberty include idiopathic precocious puberty, central nervous system disorders and McCune-Albright syndrome; pseudo-precocious precocious include breast precocious puberty, precocious puberty and tumor. Combined with clinical features, discussed the true and pseudo-precocious clinical differential diagnosis. With chlormadinone treatment of true precocious puberty in 43 cases,