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作者报道60例婴儿用高效价HBIG与乙肝疫苗双重免疫阻断HBV母婴传播的效果,其保护率为87.7％(除外脐血HBsAg阳性婴儿后为100％)。本文对不同免疫程序方案、HBlG效价、孕母HBeAg与HBsAg滴度等因素对免疫效果的影响作了探讨,强调制定统一免疫方案的重要性与迫切性。
The authors reported the effect of blocking the mother-to-child transmission of HBV by double immunization with high titer HBIG and hepatitis B vaccine in 60 infants with a protection rate of 87.7% (100% except for HBsAg positive infants with cord blood). In this paper, the effects of different immunization protocols, HBlG titer, HBsAg and HBsAg titer of pregnant women on the immune effect were discussed, emphasizing the importance and urgency of developing a unified immunization program.