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目的:对硒联合抑亢丸、甲巯咪唑治疗桥本甲状腺炎性甲亢疗效进行观察与分析。方法:找出240例桥本甲状腺炎性甲亢,并且将他们随机分为4个小组:A组的患者是单独服用甲巯咪唑的,B组则是将甲巯咪唑与抑亢丸联合的小组,C组就是硒联合甲巯咪唑组,剩余的D组就是硒联合抑亢丸、甲巯咪唑组[1]。然后对这些小组的患者分别进行观察,得知他们治疗前后的症状。结果:A组的总有效率达到60.2%,B组的总有效率达到70.1%,C组总有效率为60.5%,D组总有效率为80.10%,B、D组的总有效率相对A、C组而言要多的多(P均<0.05);每个小组治疗后的FT3、FT4、TGAb、TPOAb相对治疗前而言都要低,(P均<0.05),但是在这四组中D组下降是最快的,并且和B、C组P后得知他们的p值均<0.05;B、D组患者的甲状腺肿以及突眼的改善状况相对A、C组要好(P均<0.05)。结论:硒联合抑亢丸及甲巯咪唑治疗治疗桥本氏甲状腺炎性甲亢疗效是非常可观的,在一定程度上可以调节体内免疫。
Objective: To observe and analyze the therapeutic effect of selenium combined with Yokening pill and methimazole on Hashimoto’s thyroiditis. METHODS: Two hundred and forty Hashimoto’s thyroiditis hyperthyroidisms were identified and randomly divided into four groups: patients in group A received methimazole alone, and group B received the combination of methimazole and yikang pill , Group C is selenium combined methimazole group, the remaining group D is selenium joint inhibition Kangwan pill, methimazole group [1]. The patients in these groups were then observed and their symptoms before and after treatment were observed. Results: The total effective rate of group A was 60.2%, the total effective rate of group B was 70.1%, the total effective rate of group C was 60.5% and the total effective rate of group D was 80.10% (P <0.05). The FT3, FT4, TGAb and TPOAb in each group were lower than those before treatment (all P <0.05), but in the four groups In group D, the decrease was the fastest, and in group B and C, the p values were all less than 0.05. The improvement of goiter and exophthalmos in group B and D was better than that in group A and C (P <0.05). Conclusion: The therapeutic effect of selenium combined with Yokening pill and methimazole on Hashimoto’s thyroiditis with hyperthyroidism is very significant, and to a certain extent, it can regulate the immunity in vivo.