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目的:观察阿司匹林肠溶片联合氯吡格雷治疗冠心病心绞痛的效果及安全性。方法:选取2013年9月至2015年9月期间于我院治疗的120例冠心病心绞痛患者,以入院时间先后顺序将其平均分成对照组和观察组,对照组给予阿司匹林肠溶片治疗,观察组给予阿司匹林肠溶片和氯吡格雷联合治疗,对两组的治疗效果和安全性进行比较。结果:观察组的临床治疗效果和心电图改善总有效率均明显高于对照组(P<0.05)。在治疗期间两组均无不良反应发生,用药后患者肝肾功能、血液系统并未发生异常。结论:对冠心病心绞痛患者进行阿司匹林肠溶片和氯吡格雷联合治疗效果显著,安全性高,值得推广。
Objective: To observe the efficacy and safety of aspirin enteric-coated tablets combined with clopidogrel in the treatment of angina pectoris. Methods: From September 2013 to September 2015 in our hospital during the treatment of 120 patients with coronary heart disease angina pectoris, the order of admission time was divided into control group and observation group, the control group was given aspirin enteric-coated tablets, observation Group given aspirin enteric-coated tablets and clopidogrel combination therapy, the treatment effect and safety of the two groups were compared. Results: The clinical efficacy and the total effective rate of ECG in the observation group were significantly higher than those in the control group (P <0.05). During the treatment, no adverse reactions occurred in both groups. After treatment, the liver and kidney function and blood system did not abnormal. Conclusion: The combination therapy of aspirin enteric-coated tablets and clopidogrel in patients with coronary heart disease and angina pectoris has significant effect, high safety and worthy of promotion.