下咽及颈段食管癌的手术治疗

来源 :中华胸心血管外科杂志 | 被引量 : 0次 | 上传用户:xfengxue
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的 探讨下咽及颈段食管癌的手术疗效及颈段食管重建的方法。方法  1980年至 2 0 0 0年 6月对 86例下咽及颈段食管鳞状细胞癌进行了外科治疗。下咽癌的切除率为 97 4% (37/38例 ) ,食管重建包括喉及肿瘤切除后食管与口底吻合 4例 ,咽、喉及颈段食管切除后用颈阔肌皮瓣重建 15例 ,游离空肠间插 3例 ,全咽、全喉、全食管切除后用胃重建 12例 ,3例未行喉切除者采用食管与咽部直接吻合、颈阔肌皮瓣及用胃重建食管各 1例。颈段食管癌的切除率为 91 7% (4 4/4 8例 ) ,均采用非开胸食管拔脱后用胃重建食管。结果 术后发生并发症在胃重建组有 5 7例 (35 % ) (包括 1例术后死于心力衰竭 )、游离空肠组 1例 (33 3% ) ,颈阔肌皮瓣重建组 3例 (18 8% )。随访 6~ 10 8个月 (平均 5 7个月 ) ,下咽癌的 1、3、5年生存率分别为 80 6 %、6 0 0 %和 31 6 % ,颈段食管癌分别为 70 7%、9 5 %和 0。结论 下咽及颈段食管癌的切除率甚高 ,但下咽癌的远期疗效明显优于颈段食管癌 ,咽、喉及颈段食管切除后采用颈阔肌皮瓣重建是一种安全、有效的手术方法 ,并发症少 ,远期效果优良 Objective To investigate the surgical treatment of hypopharynx and cervical esophageal carcinoma and the method of cervical esophageal reconstruction. Methods From 1980 to June 2000, 86 cases of pharyngeal and cervical esophageal squamous cell carcinoma were treated surgically. The resection rate of hypopharyngeal carcinoma was 97 4% (37/38 cases). Esophageal reconstruction included an esophageal and alveolar bottom anastomosis in 4 cases after resection of the larynx and tumor, reconstruction of the pharynx, larynx, and cervical esophagectomy using a platysma myocutaneous flap 15 Cases, free jejunostomy in 3 cases, total resection of the pharynx, total laryngectomy, total esophagectomy, reconstruction of 12 cases with gastrectomy, 3 cases without laryngectomy, direct esophageal and pharyngeal anastomosis, platysma myocutaneous flap and reconstruction of esophagus with stomach One case each. The resection rate of cervical esophageal cancer was 91 7% (44/48). Both of them were reattached using a non-opening esophagus and reconstructed with the stomach. Results Postoperative complications occurred in 57 (35.5%) patients in the gastric remodeling group (including 1 patient died of heart failure after operation), 1 patient (33. 3%) in the free jejunum group, and 3 patients with platysma myocutaneous flap reconstruction group. (18 8%). During follow-up of 6 to 10 8 months (mean, 5 7 months), the 1-, 3-, and 5-year survival rates of hypopharyngeal cancer were 80.6%, 60%, and 316%, respectively, and cervical esophageal cancer was 70. %, 95%, and 0. Conclusion The resection rate of hypopharyngeal and cervical esophageal cancer is very high, but the long-term efficacy of hypopharyngeal carcinoma is significantly better than that of cervical esophageal cancer. It is safe to use platysma myocutaneous flap reconstruction after esophagectomy of pharynx, larynx and neck. , Effective surgical methods, less complications, excellent long-term results
其他文献
8月22日 晴  我呢,非常爱问问题,问题没完没了,非问得别人无言以对为止。和妈妈要去看电影,我问:“什么电影?什么内容?好看不好看?是谁主演?中国片还是外国片?”妈妈说:“这些问题我一个也回答不出来,你看了才知道。”  可是妈妈又说看电影去不了了,我很难过地问妈妈:“为什么?”妈妈说:“我去开会。”我又问:“什么会?为什么早不开晚不开?你有没有问可以不可以请假?”妈妈被我问得神魂颠倒了。  爸爸
舞蹈培训    无效退款  一分钟学会    The training class opens today.The training fee is 30% off!
目的了解在吲哚美辛诱导的K562细胞凋亡过程中半胱天冬酶3,8的表达、活化情况及亚细胞定位;细胞内游离钙离子浓度([fCa2+]i)变化及其机制;并探讨其凋亡调控是否依赖于环氧化酶(COX)的活性抑制。方法用共聚焦激光扫描显微镜(LSCM)观察在吲哚美辛诱导凋亡过程中K562细胞内半胱天冬酶3,8的变化及亚细胞定位,并用Western blot分析其蛋白质的表达、活化情况;用钙荧光探针结合LSCM
有诗词美文、有每日实录,还有难题咨询和批评建议。每天一大早,浙江省宁波市鄞州下应中心小学陈彩萍老师都要批阅一叠特殊的家庭作业———38份家长日记。阅后写上评语,或者开始着手其中的一些难题。  据了解,从2008年11月8日开始,陈彩萍便尝试着让一年级新生家长每天记日记,和孩子一起写下学习生活中的点点滴滴。经过多年坚持和努力,家长日记已有上千册,粗略字数统计就不少于400万字。  陈彩萍老师说,成长