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目的:观察生大黄与乳果糖联合应用对肝功能衰竭的疗效。方法:将2013年6月至2014年3月东南大学附属第二医院重症监护病房(ICU)收治的42例肝衰竭患者随机分为4组,其中对照组患者10例不使用以上两种药物,余治疗一致;单用生大黄或乳果糖患者各10例;两者联合应用治疗患者12例。观察患者意识状态以及测定其血氨水平。结果:生大黄与乳果糖联合应用组有效率75%,乳果糖应用组有效率60%,生大黄应用组有效率60%,对照组有效率40%。结论:生大黄与乳果糖联合应用对肝功能衰竭具有一定的治疗作用。
Objective: To observe the curative effect of combined application of rhubarb and lactulose on liver failure. Methods: From June 2013 to March 2014, 42 patients with liver failure admitted to the Second Affiliated Hospital of Southeast University from ICU were randomly divided into 4 groups, of which 10 patients in the control group did not use the above two drugs, I treatment consistent; single use of rhubarb or lactulose in patients with 10 cases; the two combined treatment of patients in 12 cases. Observe patient’s state of consciousness and measure their blood ammonia level. Results: Rhubarb and lactulose combined application group was 75% effective, lactulose application group 60%, rhubarb application group 60%, control group 40%. Conclusion: The combined application of rhubarb and lactulose has a certain therapeutic effect on liver failure.