患者女,26岁,因41~2周妊娠,脐绕颈1周于1996年7月19日入院待产。于7月20日22:05侧切加低位产钳助娩一男婴。为预防感染,于次日9:00给妥布霉素8万~U肌肉注射,每日2次,患者无不良反应。16:00又给妥布霉素的,约30分钟后,患者突然全身发冷、寒战、高热。立即给予地塞米松5mg、异丙嗪25mgim,20分钟后症状逐渐缓解。 讨论:妥布霉素为氨基甙类抗生素,主要用于葡 Female patient, 26 years old, because of 41 to 2 weeks of pregnancy, umbilical cord neck 1 week in July 19, 1996 admitted to hospital. At 20:02 on July 20, cut plus low forceps to give birth to a baby boy. In order to prevent infection, tobramycin 80,000 ~ U intramuscular injection at 9:00 the next day, 2 times a day, patients without adverse reactions. 16:00 to tobramycin, about 30 minutes later, the patient suddenly chills, chills, fever. Immediately given dexamethasone 5mg, promethazine 25mgim, 20 minutes after the symptoms gradually eased. Discussion: Tobramycin is an aminoglycoside antibiotic, mainly used in Portugal