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目的探讨喘可治注射液两种给药方式治疗婴幼儿毛细支气管炎的临床疗效对比。方法将179例毛细支气管炎患儿随机分为两组,在常规对症支持治疗的基础上,观察组氧气驱动雾化吸入0.9%氯化钠溶液2ml+喘可治注射液1ml,对照组给药喘可治注射液1ml肌肉注射,观察两组患者临床疗效。结果临床总有效率为观察组95.6%,对照组85.9%,差异显著,具有统计学意义(P<0.05);观察组患者咳嗽和双肺干湿性啰音消失时间及平均住院时间皆少于对照组,两组差异性显著(P<0.05)。结论喘可治注射液两种不同的给药途径均是治疗婴幼儿毛细支气管炎的有效方法,但喘可治注射液雾化吸入疗效优于肌肉注射,而且安全有效,患儿易于接受,值得在儿科临床推广应用。
Objective To investigate the clinical efficacy of two therapeutic modes of Chuankezhi injection in the treatment of infantile bronchiolitis. Methods 179 children with bronchiolitis were randomly divided into two groups. On the basis of routine symptomatic and supportive treatment, the rats in observation group were given inhalation of 0.9% sodium chloride solution 2ml + Injection can be treated 1ml intramuscular injection, the clinical efficacy of two groups were observed. Results The total clinical effective rate was 95.6% in the observation group and 85.9% in the control group, with significant difference (P <0.05). The disappearance time and the average length of stay of cough and pulmonary wet-dry rales in the observation group were all less than The difference between the two groups was significant (P <0.05). Conclusion Two different routes of administration for Chuankezhi injection are effective methods for the treatment of bronchiolitis in infants. However, chuankezhi injection is superior to intramuscular injection in atomizing inhalation and is safe and effective, which is worthy to be accepted by children In pediatric clinical application.