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目的调查武汉地区不同规模医疗机构抗菌药物使用情况。方法采用横断面调查住院患者的抗菌药物使用情况。结果 33所医疗机构36 222例住院患者的抗菌药物使用率为39.94%,其中21.56%为治疗性用药,14.88%为预防性用药,3.51%为同时兼有治疗和预防性用药;使用一种抗菌药物者占28.12%,二联用药者占10.78%,三联及以上用药者占1.04%,64.25%的治疗用药患者送标本进行了细菌培养;Ⅰ类切口手术抗菌药物使用率为58.88%,43.00%为预防用药。结论武汉地区医疗机构抗菌药物使用趋于合理,但Ⅰ类切口手术预防性用药较多,提示要进一步加强抗菌药物合理应用的管理。
Objective To investigate the use of antibacterials in medical institutions of different sizes in Wuhan. Methods The cross-sectional investigation of inpatients’ antimicrobial use was conducted. Results The antibacterial drug use rate of 36 222 hospitalized patients in 33 medical institutions was 39.94%, of which 21.56% were for therapeutic use, 14.88% were for prophylactic use, 3.51% were for both therapeutic and prophylactic use, Drugs accounted for 28.12%, two drug users accounted for 10.78%, triple and above drug users accounted for 1.04%, 64.25% of patients treated with drug delivery bacterial culture; Ⅰ class incision surgery antibacterials utilization rate of 58.88%, 43.00% For the prevention of medication. Conclusion The use of antimicrobial agents in medical institutions in Wuhan tends to be reasonable. However, the preventive administration of type Ⅰ incision surgery is more, suggesting that we should further strengthen the rational management of antimicrobial agents.