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目的：观察低渗口服补液盐联合锌制剂治疗小儿轮状病毒腹泻的临床疗效。方法将107例4月~5岁的轮状病毒腹泻患儿随机分为三组，在腹泻常规治疗的基础之上，A组给予ORSⅡ，B组给予ORSⅢ，C组给予ORSⅢ联合锌制剂，治疗后观察各组脱水纠正的情况、以及治疗过程中腹泻症状改善的时间、腹泻的总病程以及各组改用静脉补液治疗的比例以比较三组的临床疗效。结果三组总有效率分别为66.7%、89.1%、95.0%，A组与C组差异有统计学意义（<0.01）。结论低渗口服补液盐联合锌制剂治疗小儿轮状病毒腹泻能够改善临床症状，缩短病程，疗效肯定。“,”Objective To observe the clinical effect of the treatment of children with rotavirus diarrhea by the combination of the low osmotic oral liquid and the zinc preparation. Methods 107 cases of 4 months to 5 years round rotavirus diarrhea were randomly divided into three groups, on the basis of routine treatment of diarrhea, group A give ORS II, Group B give ORS III, group C give ors III combined with zinc preparations. After treatment, observe correct dehydration in each group, and treatment of abdominal diarrhea symptom improvement time, diarrhea with the whole course as well as the groups use the proportion of intravenous fluid therapy on the clinical efficacy of the three groups were compared. Results The total effective rates of the three groups were 66.7%, 89.1%, 95%, A group and C group were statistically significant ( < 0.01). Conclusion The treatment of infantile rotavirus diarrhea with low osmotic oral fluid infusion combined with zinc preparation can improve the clinical symptoms and shorten the course of disease.