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目的探讨唇裂红唇的形态学特点,为手术治疗提供实验依据。方法观测48例唇裂患者红唇外观形态特征,HE染色观察干湿性红唇组织结构。结果①Ⅲ度单侧唇裂患侧红唇最厚点厚度为(3.48±0.41)mm,明显小于Ⅱ度唇裂(P<0.05);②双侧唇裂前唇上部宽度明显小于下部,前唇正中的厚度明显大于左右侧(P<0.05);③干性红唇上皮棘层和固有层较薄,毛细血管丰富,粘膜下层厚且有大量腺体,肌层较致密;湿性红唇固有层毛细血管少,粘膜下层较薄,腺体少,肌层疏松。结论单侧唇裂患侧红唇厚度可能与裂隙大小有关,双侧唇裂前唇外观形态与左右侧有差异,唇裂干湿性红唇组织结构存在明显差异,术中应加以注意。
Objective To investigate the morphological characteristics of cleft lips and provide experimental evidence for surgical treatment. Methods Forty - eight patients with cleft lip were observed morphologically. The histological changes of the wet and dry lips were observed by HE staining. Results The thickness of the thickest point of the unilateral cleft lip of the third degree was (3.48 ± 0.41) mm, which was significantly smaller than that of the second degree cleft lip (P <0.05). ② The width of the anterior lip of the cleft lip was significantly smaller than that of the lower part, (P <0.05) .③The stratum spinosum and lamina propria of dry red lip epithelium are thinner, the capillaries are rich, the submucosa is thick and has a large number of glands, , Submucosa thinner, less glandular muscle relaxation. Conclusion The thickness of the affected side of the unilateral cleft lip may be related to the size of the cleft. The morphology of the anterior lip of the bilateral cleft lip is different from that of the left and right lip. There are significant differences in the organizational structure of the cleft lip and wet lip, which should be paid attention to in the operation.