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从大花红景天Rhodiola crenulata (HK.f.et thoms)H.Ohba的乙酸乙酯提取物中分离出12个多元酚类化合物。其中六个经光谱分析和化学方法鉴定为没食子酸(gallic acid,1),酪醇(p-tyrosol,2),6-氧-没食子酰基红景天甙(6-O-galloylsalidroside,3),1,2,3,4,6-五氧-没食子酰基-β-D-吡喃葡萄糖(1,2,3,4,6-penta-O-galloyl-β-D-gluco pyranoside,4),草质素-7-氧-α-L-吡喃鼠李糖甙(rhodionin,5),草质素-7-氧-(3-氧-β-D-吡喃葡萄糖基)-α-L-吡喃鼠李糖甙(rhodiosin,6),1和4具有抗毒肝素的活性,4还有抗脂质过氧化的活性,2,5,6具有提高机体抗逆境能力的活性。
Twelve polyhydric phenolic compounds were isolated from the ethyl acetate extract of rhodiola rhodiola crenulata (HK.f. et thoms) H. Ohba. Six of them were identified as gallic acid (1), tyrosol (2), and 6-O-galloylsalidroside (3) by spectral analysis and chemical methods. 1,2,3,4,6-pentaoxy-galloyl-β-D-glucopyranose (1,2,3,4,6-penta-O-galloyl-β-D-gluco pyranoside, 4), Terpene-7-oxo-α-L-rhamnofuranoside (rhodionin, 5), 7-oxo-(3-oxo-β-D-glucopyranosyl)-α-L - rhodorsin (6), 1 and 4 have anti-heparin activity, 4 also have anti-lipid peroxidation activity, 2, 5, and 6 have the activity of improving the body’s resistance to stress.