前言系统性红斑狼疮(SLE)患者体内可出现多种自身抗体,其中以抗双链DNA(dsDNA)抗体特异性较高。目前,国内外都将抗dsDNA抗体的检测作为SLE的诊断标准之一。检测抗dsDNA抗体的方法较多,但各具利弊。比较言之,以间接免疫荧光试验较敏感特性,简便实用。近年来,国外有人应用血锥虫或血鞭毛虫作为抗原,以间接免疫荧光技术检测抗dsDNA抗体,发现此类底物特异性较好。国内应用马疫、短膜虫也获成功。但由于它们来 Preface Multiple autoantibodies can occur in patients with systemic lupus erythematosus (SLE), of which anti-dsDNA antibodies are more specific. At present, anti-dsDNA antibody detection at home and abroad as one of the diagnostic criteria for SLE. There are many ways to detect anti-dsDNA antibodies, but each has its own advantages and disadvantages. In short, indirect immunofluorescence test more sensitive features, simple and practical. In recent years, some people abroad use trypanosomiasis or blood flagellates as antigens, indirect immunofluorescence detection of anti-dsDNA antibodies and found that such substrate specificity is better. Domestic application of the plague, Membrane also succeeded. But because of them