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目的探讨自拟复方绿豆甘草汤洗胃和参麦注射液治疗乌头碱中毒的效果。方法 100例急性乌头碱类药物中毒患者,随机分为对照组和治疗组,各50例。对照组采用洗胃、导泻、大量补液、纠正心律失常对症支持等治疗。治疗组在对照组治疗的基础上,洗胃用自拟复方绿豆甘草汤配合参麦注射液40~100 ml加入5%葡萄糖(GS)注射液500 ml中静脉滴注。比较两组治疗效果。结果经治疗,治疗组总有效率为94.0%,对照组为74.0%,两组比较差异具有统计学意义(P<0.01)。结论早期应用自拟复方绿豆甘草汤洗胃和参麦注射液治疗乌头碱中毒可提高抢救成功率。
Objective To investigate the curative effect of aconite poisoning by self-made compound mung bean and licorice soup lavage and Shenmai injection. Methods 100 cases of acute aconitine poisoning were randomly divided into control group and treatment group, 50 cases each. The control group used gastric lavage, catharsis, massive rehydration, correction of symptomatic arrhythmia supportive treatment. The treatment group in the control group based on the treatment, gastric lavage with self-compound Fang mung bean and licorice soup with Shenmai injection 40 ~ 100 ml 5% glucose (GS) injection 500 ml intravenous infusion. Compare the treatment effect of two groups. Results After treatment, the total effective rate was 94.0% in the treatment group and 74.0% in the control group, with significant difference between the two groups (P <0.01). Conclusion Early application of compound mung bean and licorice soup gastric lavage and Shenmai injection aconitine poisoning can improve the success rate of rescue.