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1例64岁男性患者因冠心病、急性前间壁心肌梗死给予阿司匹林300mg,1次/d、氯吡格雷75mg,1次/d,静脉滴注150万U尿激酶,并给予硝酸异山梨酯、美托洛尔、洛伐他汀。1个月后阿司匹林减量至100mg,1次/d,氯吡格雷剂量不变。7个月后患者出现发热、咽痛,血常规示WBC1.6×109/L,PLT82×109/L。停用氯吡格雷,其他治疗不变,7d后白细胞及血小板计数恢复正常。继续使用阿司匹林、美托洛尔及洛伐他汀,随访1年无复发。
A 64-year-old male patient was given aspirin 300 mg once daily, clopidogrel 75 mg once daily, and 1.5 million Urokinase intravenously for coronary heart disease and acute anterior myocardial infarction. Metoprolol, lovastatin. After 1 month aspirin reduced to 100mg, 1 / d, unchanged dose of clopidogrel. Seven months later, the patient developed fever and sore throat. The blood showed WBC1.6 × 109 / L and PLT82 × 109 / L. Clopidogrel discontinuation, other treatment unchanged, after 7d white blood cell and platelet count returned to normal. Continue to use aspirin, metoprolol and lovastatin, followed up for 1 year without recurrence.