金黄色葡萄球菌的黏附和内在化,在其感染和逃逸体液免疫过程中起着十分重要的作用。金黄色葡萄球菌能产生许多细胞表面定植因子,包括纤连蛋白结合蛋白(FnBP)、纤维蛋白原结合蛋白以及弹性蛋白等。FnBP在细菌黏附和内在化中的作用已较为肯定,但无FnBP表达的细菌仍有低水平的内在化,提示有其他内在化途径的存在。 Staphylococcus aureus adhesion and internalization, in its infection and escape humoral immune process plays a very important role. Staphylococcus aureus can produce many cell surface colonization factors, including fibronectin binding protein (FnBP), fibrinogen binding protein and elastin. The role of FnBP in bacterial adhesion and internalization has been relatively positive, but there is still a low level of internalization of FnBP-expressing bacteria, suggesting the existence of other internalized pathways.