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目的探讨新生儿重症监护病房(NICU)早产儿医院获得性肺炎的危险因素,为临床降低早产儿发生医院获得性肺炎提供理论依据,并制定预防控制措施。方法研究医院2010年1月-2011年4月NICU发生与未发生医院获得性肺炎的患儿,分为病例组和对照组,对影响因素进行logistic多因素回归分析。结果住NICU天数,病例组(26.08±2.42)d,对照组为(9.52±0.66)d;危重评分,病例组(90.60±0.75)分,对照组为(96.72±0.62)分;羊水性状(OR=15.385,P=0.020)、新生儿危重评分(OR=1.315,P=0.001)、气管插管(OR=26.399,P=0.022)、胃管喂养(OR=9.174,P=0.045)、住院NICU天数(OR=1.179,P=0.039)是早产儿患医院获得性肺炎的危险因素。结论早产儿患医院获得性新生儿肺炎有其自身器官发育不完全的因素,也存在外部潜在的危险因素,应该加强对早产儿患医院获得性肺炎危险因素的防护,并加强医院感染的监测,降低早产儿医院获得性肺炎的发生率。
Objective To explore the risk factors of hospital-acquired pneumonia in neonatal intensive care unit (NICU) premature infants and to provide a theoretical basis for reducing the incidence of hospital-acquired pneumonia in premature infants and to develop preventive and control measures. Methods The study hospital from January 2010 to April 2011 NICU with and without hospital-acquired pneumonia in children, divided into case group and control group, the influencing factors were analyzed by logistic multivariate regression analysis. Results The number of days of NICU in hospital cases was (26.08 ± 2.42) d and (9.52 ± 0.66) days in control group. The critical score was 90.60 ± 0.75 in case group and 96.72 ± 0.62 in control group. (OR = 1.315, P = 0.001), endotracheal intubation (OR = 26.399, P = 0.022), gastric tube feeding (OR = 9.174, P = 0.045) The number of days (OR = 1.179, P = 0.039) was a risk factor for hospital-acquired pneumonia in preterm infants. Conclusions Hospital-acquired neonatal pneumonia in preterm infants has incomplete organ development and potential external risk factors. It is necessary to strengthen the protection of hospital-acquired pneumonia risk factors in preterm infants and to strengthen the monitoring of nosocomial infections. Reduce the incidence of hospital-acquired pneumonia in preterm infants.