子宫内膜癌是常见的妇科恶性肿瘤，近年来其发病率逐渐上升并趋于年轻化。虽然经过以手术为主的综合治疗，患者能获得良好的存活率，但却失去了内分泌生殖能力，因而越来越多的未生育年轻女性要求保留生育功能。部分孕激素受体阳性的子宫内膜癌患者经孕激素治疗后成功妊娠，而孕激素受体阴性的患者目前仍缺乏保留生育功能的有效疗法。因此，寻找新的有效治疗手段极为重要。分子靶向治疗是在细胞分子水平上，对已经明确的致癌位点进行药物治疗使肿瘤细胞特异性死亡，而不会波及肿瘤周围的正常组织细胞。所以，探究分子靶向治疗在子宫内膜癌治疗中的作用可能是未来研究趋势。“,”Endometrial cancer is a common malignant tumor,the incidence of which has increased and the patients tend to be younger in recent years.Although patients can obtain good survival rate by comprehen-sive treatment based on surgery,they also lose the ability of reproductive endocrine.Therefore,more and more nulliparous young women require preservation of fertility.Some of the endometrial cancer patients have suc-cessful pregnancy after treatment by progesterone whose progesterone receptors are positive .However, those patients with negative progesterone receptor negative are still needing effective therapy to preserve fertility .So looking for new effective treatment is very important for those patients .Molecular targeted therapy is aimed at clear carcinogenic sites for drug treatment on the molecular level to make specific death of the cancer cells, without affecting the normal tissue surrounding the tumor cells.Therefore,to explore the role of molecular tar-geted therapy of endometrial cancer may be the trend of future research .