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精索静脉曲张是男性不育症最常见的原因。生育力低下的人中21—40%有精索静脉曲张,是正常人的3倍。众多报告发现精索静脉曲张的低育男性有精液异常,包括精子数少、活动力弱、细头精子和不成熟精子增多。Macleod认为精索静脉曲张病人的精液是压抑型(stross pattern)。组织学检查光镜可见生精上皮变薄、精子生成受阻及生精细胞的变性坏死,电镜可见精子成熟受阻以及支持细胞与精细胞交界处异常的复合物。因此有人推测,由于组织学的改变可引起睾丸容积的变化。作者用睾丸测量器测定了83例正常人和291例
Varicocele is the most common cause of male infertility. 21-40% of people with fertility have varicocele, which is 3 times of that of normal people. Many reports found that infertile men with varicoceles have abnormal semen, including fewer sperm count, less motility, increased sperm count and immature sperm. Macleod believes that sperm in patients with varicoceles are the stross pattern. Histopathological examination shows thinning of the seminiferous epithelium, spermatogenesis and degeneration and necrosis of spermatogenic cells. Electron microscopy shows that spermatozoon maturation is blocked and abnormal complexes of supporting cells and spermatid junction are observed. Therefore, it was speculated that due to changes in histology can cause changes in testicular volume. The authors measured 83 normal subjects and 291 subjects with a testis tester