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目的研究高龄老人血浆高敏C反应蛋白(hsC-RP)与糖尿病的关系。方法通过问卷调查、身体测量和实验室检测,收集并分析499位90岁及以上高龄老人基本状况、生活方式、身体指标及血浆hsC-RP、TC、TG、FPG水平等信息。结果 logistic回归显示,在调整多种混杂因素后,hsC-RP与糖尿病仍呈显著正向关系(P<0.05),OR(95%CI)值为1.94(1.08,3.48)。多元线性回归结果也表明,hsC-RP与FPG水平显著相关(P<0.01)。本研究还发现在高龄老人中TG仍是糖尿病独立的危险因素(P<0.05)。结论高龄老人hsC-RP与糖尿病具有独立、显著的正向关系。
Objective To study the relationship between plasma high-sensitivity C-reactive protein (hsC-RP) and diabetes mellitus in the elderly. Methods The questionnaires, body measurements and laboratory tests were used to collect and analyze the information of 499 elderly people aged 90 years and above, their lifestyle, physical indexes and plasma hsC-RP, TC, TG and FPG levels. Results Logistic regression showed that there was a significant positive correlation between hsC-RP and diabetes (P <0.05) and OR (95% CI) of 1.94 (1.08, 3.48) after adjusting for various confounding factors. Multiple linear regression also showed that hsC-RP was significantly associated with FPG (P <0.01). The present study also found that TG was still an independent risk factor for diabetes in elderly people (P <0.05). Conclusion There is an independent and significant positive relationship between hsC-RP and diabetes in the elderly.