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我院于1994年2月~1997年3月,在胃镜下局部注射加全身联合化疗,治疗晚期食管贲门癌18例,收到了良好的效果。1 对象和方法1.1 对象 18例中男13例,女5例,年龄48岁~79岁。均经食管钡餐、胃镜及病理证实为Ⅲ期~Ⅳ期食管贲门癌。鳞癌12例,腺癌6例。进行性吞咽困难9例,胸骨后疼痛5例,不能进食进水3例,恶病质1例。内镜下肿块型菜花样隆起8例,环形狭窄5例,溃疡浸润样改变5例。全部病人治疗前后进行常规体检、胃镜、食管钡透,血常规、血小板、肝肾功能等有关检查。
From February 1994 to March 1997, our hospital underwent local injection plus systemic chemotherapy to treat 18 cases of advanced esophageal and cardiac cancers, and received good results. 1 Subjects and methods 1.1 Subjects 18 cases of 13 males and 5 females, aged 48 to 79 years old. All cases were esophageal barium meal, gastroscope and pathology confirmed as stage III to IV esophageal and cardiac cancer. There were 12 squamous cell carcinomas and 6 adenocarcinomas. There were 9 cases of progressive dysphagia, 5 cases of poststernal pain, 3 cases of inability to eat water, and 1 case of cachexia. Under the endoscopy, there were 8 cases of mass-shaped calyx uplift, 5 cases of annular stenosis, and 5 cases of ulcer-like infiltration. Before and after treatment, all patients performed routine physical examination, gastroscopy, esophageal fistula, blood routine, platelet, liver and kidney function tests.