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目的观察高效抗反转录病毒治疗(HAART)对艾滋病患者早期生活质量的影响。方法 52例艾滋病患者行HAART,同时采用诺丁汉健康量表(NHP)对患者的生命质量进行调查评估。结果 52例艾滋病患者治疗12个月后体重和CD4+T淋巴细胞较治疗前显著增加(P<0.05)。NHP维度分析显示,患者躯体活动、精力状况、疼痛、睡眠和情感反应NHP综合积分值在治疗后显著改善(P<0.05),但社会孤独感状况改善不明显(P>0.05)。结论 HAART可以提高艾滋病患者CD4+T淋巴细胞计数和增加体重,改善近期生活质量。
Objective To observe the effect of HAART on early life quality of AIDS patients. Methods 52 AIDS patients underwent HAART. The quality of life of the patients was evaluated by the Nottingham Health Scale (NHP). Results After 52 months of treatment, the body weight and CD4 + T lymphocytes of AIDS patients increased significantly (P <0.05) after treatment for 12 months. The NHP dimension analysis showed that the scores of physical activity, mental status, pain, sleep and emotional response were significantly improved after treatment (P <0.05), but the improvement of social loneliness was insignificant (P> 0.05). Conclusions HAART can increase CD4 + T lymphocyte count and increase body weight of AIDS patients and improve the quality of life in the near future.