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目的探讨乳酸杆菌胶囊预防外阴阴道假丝酵母菌病复发的临床疗效。方法选择我院自2012年9月至2013年9月门诊治疗的116例外阴阴道假丝酵母菌病患者,随机分为观察组和对照组各58例,观察组给予碳酸氢钠联合克霉唑栓治疗后,再用乳酸杆菌胶囊巩固治疗3疗程,对照组给予碳酸氢钠联合克霉唑栓治疗。结果观察组的复发率为3.4%,对照组的复发率为31.0%。两组比较,差异具有统计学意义(P<0.05)。结论乳酸杆菌胶囊在预防外阴阴道假丝酵母菌复发的临床疗效显著,药物安全可靠,无毒副作用,有利于患者接受,值得临床推广应用。
Objective To investigate the clinical efficacy of Lactobacillus capsules in preventing the recurrence of vulvovaginal candidiasis. Methods One hundred and sixty-six patients with vulvovaginal candidiasis who were treated in our hospital from September 2012 to September 2013 were randomly divided into observation group (58 cases) and control group (58 cases). The observation group was given sodium bicarbonate combined with clotrimazole After the suppository treatment, Lactobacillus capsules were used to consolidate for 3 courses of treatment. The control group was given sodium bicarbonate combined with clotrimazole suppository. Results The recurrence rate was 3.4% in the observation group and 31.0% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion The clinical efficacy of Lactobacillus capsules in preventing the recurrence of vulvovaginal candidiasis is significant, the drugs are safe, reliable and non-toxic and side-effect, which is beneficial to patients’ acceptance and worthy of clinical application.